Scientists at the Ural Federal University named after the first President of Russia B. N. Yeltsin. Yeltsin Federal University (UrFU) synthesized chemical compounds that combat neuronal degeneration in Alzheimer's, Parkinson's and other brain pathologies, writes Lenta.ru.
"Our compounds activate the synthesis of special heat shock proteins and cause them to accumulate in the cell. Proteins of this type allow to secure neuronal tissue from an excess of toxic amyloids and protect cells from various types of stress, including proteotoxic stress characteristic of neurodegenerative diseases," explained Irina Utepova, professor of the department of organic and biomolecular chemistry at UrFU.
Compounds obtained in Russia have an advantageous synthesis technology and low toxicity. They have been tested on cellular models of Alzheimer's disease and secondary damage after brain injury, the university explained. In both situations, the developed substances showed a significant therapeutic effect and increased the survival of neuronal cells.
Made in Russia // Made in Russia
Author: Karina Kamalova